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l thyroxine  (MedChemExpress)
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Associated co-expressed differential proteins in placenta and plasma among pregnant women with ICP and healthy pregnant women.
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total t4  (Revvity)
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Image Search Results


Associated co-expressed differential proteins in placenta and plasma among pregnant women with ICP and healthy pregnant women.

Journal: Heliyon

Article Title: Secreted proteins in plasma and placenta as novel non-invasive biomarkers for intrahepatic cholestasis of pregnancy: A case-control study

doi: 10.1016/j.heliyon.2023.e21616

Figure Lengend Snippet: Associated co-expressed differential proteins in placenta and plasma among pregnant women with ICP and healthy pregnant women.

Article Snippet: The primary antibodies used in this study were anti -NECTIN1 (1:100 dilution, Cat. 24713-1-AP, ProteinTech), anti -SPINT1 (1:100 dilution, Cat. ab189511; Abcam), anti -SERPINA7 (1:300 dilution; Cat. 66454-1-Ig; ProteinTech), anti-CD320 (1:300 dilution; Cat. 10343-1-AP, ProteinTech), anti -ITIH3 (1:100 dilution, Cat. DF14157, Affinity), anti -ENPP2 (1:50 dilution, Cat. 14243-1-AP, ProteinTech), and anti -SERPIND1 (1:25 dilution, Cat. ab232859; Abcam, Cambridge, UK).

Techniques: Clinical Proteomics, Protease Inhibitor

Correlation analysis of co-differentially expressed protein levels between placental and plasma samples. (A) Correlation analysis of RPS7 between placental and plasma samples. (B) Correlation analysis of NECTIN3 between placental and plasma samples. (C) Correlation analysis of NECTIN1 between placental and plasma samples. (D) Correlation analysis of SPINT1 between placental and plasma samples. (E) Correlation analysis of SERPINA7 between placental and plasma samples. (F) Correlation analysis of CD320 between placental and plasma samples. (G) Correlation analysis of ITIH3 between placental and plasma samples. (H) Correlation analysis of ENPP2 between placental and plasma samples. (I) Correlation analysis of SERPIND1 between placental and plasma samples.

Journal: Heliyon

Article Title: Secreted proteins in plasma and placenta as novel non-invasive biomarkers for intrahepatic cholestasis of pregnancy: A case-control study

doi: 10.1016/j.heliyon.2023.e21616

Figure Lengend Snippet: Correlation analysis of co-differentially expressed protein levels between placental and plasma samples. (A) Correlation analysis of RPS7 between placental and plasma samples. (B) Correlation analysis of NECTIN3 between placental and plasma samples. (C) Correlation analysis of NECTIN1 between placental and plasma samples. (D) Correlation analysis of SPINT1 between placental and plasma samples. (E) Correlation analysis of SERPINA7 between placental and plasma samples. (F) Correlation analysis of CD320 between placental and plasma samples. (G) Correlation analysis of ITIH3 between placental and plasma samples. (H) Correlation analysis of ENPP2 between placental and plasma samples. (I) Correlation analysis of SERPIND1 between placental and plasma samples.

Article Snippet: The primary antibodies used in this study were anti -NECTIN1 (1:100 dilution, Cat. 24713-1-AP, ProteinTech), anti -SPINT1 (1:100 dilution, Cat. ab189511; Abcam), anti -SERPINA7 (1:300 dilution; Cat. 66454-1-Ig; ProteinTech), anti-CD320 (1:300 dilution; Cat. 10343-1-AP, ProteinTech), anti -ITIH3 (1:100 dilution, Cat. DF14157, Affinity), anti -ENPP2 (1:50 dilution, Cat. 14243-1-AP, ProteinTech), and anti -SERPIND1 (1:25 dilution, Cat. ab232859; Abcam, Cambridge, UK).

Techniques: Clinical Proteomics

Correlation analysis between ELISA and sequencing results and the validation of plasma differential proteins using ELISA. (A–E) The correlation analysis of SPINT1, SERPINA7, NECTIN1, SERPIND1, and ITIH3 between ELISA and sequencing results. (F) NECTIN1 levels in plasma samples obtained from ICP and control groups (P < 0.0001). (G) SPINT1 levels in plasma samples obtained from ICP and control groups (P < 0.0001). (H) ITIH3 levels in plasma samples obtained from ICP and control groups (P = 0.0001). (I) ENPP2 levels in plasma samples obtained from ICP and control groups (P < 0.0001). (J) SERPIND1 levels in plasma samples obtained from ICP and control groups (P < 0.0001); (****P < 0.0001, ***P < 0.001). ELISA, enzyme-linked immunosorbent assay; ICP, intrahepatic cholestasis of pregnancy.

Journal: Heliyon

Article Title: Secreted proteins in plasma and placenta as novel non-invasive biomarkers for intrahepatic cholestasis of pregnancy: A case-control study

doi: 10.1016/j.heliyon.2023.e21616

Figure Lengend Snippet: Correlation analysis between ELISA and sequencing results and the validation of plasma differential proteins using ELISA. (A–E) The correlation analysis of SPINT1, SERPINA7, NECTIN1, SERPIND1, and ITIH3 between ELISA and sequencing results. (F) NECTIN1 levels in plasma samples obtained from ICP and control groups (P < 0.0001). (G) SPINT1 levels in plasma samples obtained from ICP and control groups (P < 0.0001). (H) ITIH3 levels in plasma samples obtained from ICP and control groups (P = 0.0001). (I) ENPP2 levels in plasma samples obtained from ICP and control groups (P < 0.0001). (J) SERPIND1 levels in plasma samples obtained from ICP and control groups (P < 0.0001); (****P < 0.0001, ***P < 0.001). ELISA, enzyme-linked immunosorbent assay; ICP, intrahepatic cholestasis of pregnancy.

Article Snippet: The primary antibodies used in this study were anti -NECTIN1 (1:100 dilution, Cat. 24713-1-AP, ProteinTech), anti -SPINT1 (1:100 dilution, Cat. ab189511; Abcam), anti -SERPINA7 (1:300 dilution; Cat. 66454-1-Ig; ProteinTech), anti-CD320 (1:300 dilution; Cat. 10343-1-AP, ProteinTech), anti -ITIH3 (1:100 dilution, Cat. DF14157, Affinity), anti -ENPP2 (1:50 dilution, Cat. 14243-1-AP, ProteinTech), and anti -SERPIND1 (1:25 dilution, Cat. ab232859; Abcam, Cambridge, UK).

Techniques: Enzyme-linked Immunosorbent Assay, Sequencing, Biomarker Discovery, Clinical Proteomics, Control

Diagnostic value analysis of plasma proteins in ICP.

Journal: Heliyon

Article Title: Secreted proteins in plasma and placenta as novel non-invasive biomarkers for intrahepatic cholestasis of pregnancy: A case-control study

doi: 10.1016/j.heliyon.2023.e21616

Figure Lengend Snippet: Diagnostic value analysis of plasma proteins in ICP.

Article Snippet: The primary antibodies used in this study were anti -NECTIN1 (1:100 dilution, Cat. 24713-1-AP, ProteinTech), anti -SPINT1 (1:100 dilution, Cat. ab189511; Abcam), anti -SERPINA7 (1:300 dilution; Cat. 66454-1-Ig; ProteinTech), anti-CD320 (1:300 dilution; Cat. 10343-1-AP, ProteinTech), anti -ITIH3 (1:100 dilution, Cat. DF14157, Affinity), anti -ENPP2 (1:50 dilution, Cat. 14243-1-AP, ProteinTech), and anti -SERPIND1 (1:25 dilution, Cat. ab232859; Abcam, Cambridge, UK).

Techniques: Diagnostic Assay, Clinical Proteomics